Metabolic support by macrophages sustains colonic epithelial homeostasis

Approved

Classifications

MinEdu publication type
A1 Journal article (peer-reviewed)
Definition
Article
Target group
Scientific
Peer reviewed
Peer-reviewed
Article type
Journal article
Host publication type
Journal

Authors of the publication

Number of authors
28
Authors
Fritsch, Stephanie Deborah; Sukhbaatar, Nyamdelger; Gonzales, Karine; Sahu, Alishan; Tran, Loan; Vogel, Andrea; Mazic, Mario; Wilson, Jayne Louise; Forisch, Stephan; Mayr, Hannah; Oberle, Raimund; Weiszmann, Jakob; Brenner, Martin; Vanhoutte, Roeland; Hofmann, Melanie; Pirnes-Karhu, Sini; Magnes, Christoph; Kühnast, Torben; Weckwerth, Wolfram; Bock, Christoph; Klavins, Kristaps; Hengstschläger, Markus; Moissl-Eichinger, Christine; Schabbauer, Gernot; Egger, Gerda; Pirinen, Eija; Verhelst, Steven H. L.; Weichhart, Thomas

Publication channel information

Title of journal/series
Cell metabolism
ISSN (print)
1550-4131
ISSN (electronic)
1932-7420
ISSN (linking)
1550-4131
Publisher
Elsevier
Publication forum ID
53199
Publication forum level
3
Country of publication
United States
Internationality
Yes

Detailed publication information

Publication year
2023
Reporting year
2023
Journal/series volume number
35
Journal/series issue number
11
Page numbers
1931-1943.e8
DOI
10.1016/j.cmet.2023.09.010
Language of publication
English

Co-publication information

International co-publication
Yes
Co-publication with a company
No

Availability

Link to self-archived version
https://urn.fi/URN:NBN:fi:oulu-202401051082

Classification and additional information

MinEdu field of science classification
1182 Biochemistry, cell and molecular biology, 3111 Biomedicine
Keywords
arginase-1; homeostasis; immunometabolism; intestine; mTOR; mTORC1; macrophages; polyamines; spermine

Funding information

Funding information in the publication
Research was supported by funding from the following sources: the Austrian Science Fund (FWF) grants P34266-B (T.W.), P34023-B (T.W.), FWF Sonderforschungsbereich SFB F83 (T.W., G.E., and G.S.), the Vienna Science and Technology Fund (WWTF) grant LS18-058 (T.W.), and the Christian Doppler Laboratory Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis (G.S.). L.T. was supported by a DOC fellowship of the Austrian Academy of Sciences.

Research data information

Research data information in the publication
All data points including mass spectrometry data used to create the graphs and uncropped western blots are provided in Data S1. RNA-seq data has been deposited on NCBI GEO: GSE175992. Microbiome sequencing data has been deposited on Embl-ENA: PRJEB64866. This manuscript does not report any original code

Source database ID

WoS ID
WOS:001110915400001
Scopus ID
2-s2.0-85174571419
Other database ID
PMID: 37804836