Paratope mapping of tilvestamab, an anti-AXL function-blocking antibody, using high-throughput bacterial expression of secreted scFv-ompY fusion proteins
Approved
Classifications
MinEdu publication type
A1 Journal article (peer-reviewed)
Definition
Article
Target group
Scientific
Peer reviewed
Peer-reviewed
Article type
Journal article
Host publication type
Journal
Publication channel information
Title of journal/series
Bioscience reports
ISSN (print)
0144-8463
ISSN (electronic)
1573-4935
ISSN (linking)
0144-8463
Publisher
Portland press
Publication forum ID
52445
Publication forum level
1
Country of publication
United States
Internationality
Yes
Detailed publication information
Publication year
2025
Bibliographical publication year
2025
Reporting year
2025
Journal/series volume number
45
Journal/series issue number
10
Article number
BSR20253747
DOI
10.1042/BSR20253747
Language of publication
English
Co-publication information
International co-publication
Yes
Co-publication with a company
No
Availability
Link to online publication
Link to self-archived version
Classification and additional information
MinEdu field of science classification
1182 Biochemistry, cell and molecular biology
Keywords
antibodies; protein binding; protein conformation; receptor tyrosine kinases; recombinant proteins
Additional information
[Epub ahead of print 25 Sep 2025]
Funding information
Funding information in the publication
We acknowledge the use of the Core Facility for Biophysics, Structural Biology, and Screening (BiSS) at the University of Bergen, which has received infrastructure funding from the Research Council of Norway (RCN) through NORCRYST (grant number 245828) and NOR-OPENSCREEN (grant number 245843).
E.C. was supported by the Norwegian Research Council Industrial PhD Studentship 276844.
Research data information
Research data information in the publication
All relevant data are included within the manuscript, figures, tables, and supplementary information.
Raw data files are available from the corresponding author upon reasonable request.
Source database ID
WoS ID
WOS:001605508000001
Scopus ID
2-s2.0-105020459773
Other database ID
PMID: 41004176