Autologous atrial appendage micrografts transplanted during coronary artery bypass surgery: design of the AAMS2 randomized, double-blinded, and placebo-controlled trial

Approved

Classifications

MinEdu publication type
A1 Journal article (peer-reviewed)
Definition
Article
Target group
Scientific
Peer reviewed
Peer-reviewed
Article type
Journal article
Host publication type
Journal

Authors of the publication

Number of authors
35
Authors
Sikorski, Vilbert; Nummi, Annu; Kuuva, Aleksi; Wilkman, Erika; Rajala, Helena; Stewart, Juhani; Junttila, Juhani; Lindgren, Kai; Kervinen, Kari; Teittinen, Kari; Kohonen, Katja; Oksaharju, Kati; Okkonen, Marjo; Holmström, Miia; Lehtinen, Miia; Mulari, Severi; Taskinen, Panu; Simonen, Piia; Karvonen, Päivi; Kastell, Päivi; Kärjä-Koskenkari, Päivi; Kandolin, Riina; Kesävuori, Risto; Kaarlenkaski, Sari; Vaara, Satu; Dahlbacka, Sebastian; Syrjälä, Simo; Syväranta, Suvi; Juvonen, Tatu; Erkinaro, Tiina; Mäkelä, Tuomas; Karjalainen, Pasi; Kankuri, Esko; Vento, Antti; Nykänen, Antti

Publication channel information

Title of journal/series
Trials
ISSN (electronic)
1745-6215
ISSN (linking)
1745-6215
Publisher
Biomed central
Publication forum ID
68711
Publication forum level
1
Internationality
Yes

Detailed publication information

Publication year
2026
Bibliographical publication year
2026
Reporting year
2026
Journal/series volume number
27
Article number
97
DOI
10.1186/s13063-025-09379-4
Language of publication
English

Co-publication information

International co-publication
No
Co-publication with a company
Yes

Availability

Link to self-archived version
https://urn.fi/URN:NBN:fi:oulu-202601141199

Classification and additional information

MinEdu field of science classification
3126 Surgery, anesthesiology, intensive care, radiology, 3121 General medicine, internal medicine and other clinical medicine
Keywords
AAMs-patch; Atrial appendage; Cardiac surgery; Cell therapy; Epitranscriptomics; Heart failure; Ischemic heart disease; Micrografts; Tissue-engineering
Additional information
[Epub ahead of print 02 Jan 2026]

Funding information

Funding information in the publication
Open Access funding provided by University of Helsinki (including Helsinki University Central Hospital). This work was supported by the Finnish Foundation for Cardiovascular Research (V.S. 200174, A.V. 200196 and 220094), Government-allocated block grants to specialty area (A.V. TYH2023339, TYH2021346), Aarne Koskelo Foundation (V.S.), The Finnish Medical Foundation (V.S. 3857), The Ida Montin Foundation (V.S. 20210362), and the Emil Aaltonen Foundation (V.S. 210212 K). Open access is funded by Helsinki University Library.
Funders
Funder
Heart Research Foundation
Name of funding
-
Funding decision
200174
Funder
Heart Research Foundation
Name of funding
-
Funding decision
200196
Funder
Heart Research Foundation
Name of funding
-
Funding decision
220094
Funder
The Finnish Medical Foundation
Name of funding
-
Funding decision
3857
Funder
Emil Aaltonen Foundation
Name of funding
-
Funding decision
210212

Research data information

Research data information in the publication
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Source database ID

WoS ID
WOS:001678172800001
Scopus ID
2-s2.0-105029100291
Other database ID
PMID: 41485016