[1,2,4]Triazolo[3,4-b]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes

Approved

Classifications

MinEdu publication type
A1 Journal article (peer-reviewed)
Definition
Article
Target group
Scientific
Peer reviewed
Peer-reviewed
Article type
Journal article
Host publication type
Journal

Authors of the publication

Number of authors
17
Authors
Murthy, Sudarshan; Nizi, Maria Giulia; Maksimainen, Mirko M; Massari, Serena; Alaviuhkola, Juho; Lippok, Barbara E; Vagaggini, Chiara; Sowa, Sven T; Galera-Prat, Albert; Ashok, Yashwanth; Venkannagari, Harikanth; Prunskaite-Hyyryläinen, Renata; Dreassi, Elena; Lüscher, Bernhard; Korn, Patricia; Tabarrini, Oriana; Lehtiö, Lari

Publication channel information

Title of journal/series
Journal of medicinal chemistry
ISSN (print)
0022-2623
ISSN (electronic)
1520-4804
ISSN (linking)
0022-2623
Publisher
American chemical society
Publication forum ID
61000
Publication forum level
3
Country of publication
United States
Internationality
Yes

Detailed publication information

Publication year
2023
Reporting year
2023
Journal/series volume number
66
Journal/series issue number
2
Page numbers
1301-1320
DOI
10.1021/acs.jmedchem.2c01460
Language of publication
English

Co-publication information

International co-publication
Yes
Co-publication with a company
No

Availability

Classification and additional information

MinEdu field of science classification
1182 Biochemistry, cell and molecular biology

Funding information

Funding information in the publication
The work was supported by the Deutsche Forschungsgemeinschaft funding to BL (Lu 466/16-2), by the Magnus Ehrnrooth Foundation to S.M., and by the Academy of Finland (grant nos. 287063 and 294085) and by Sigrid Juselius ́and Jane and Aatos Erkko foundations to L.L.
Funders
Funder
Research Council of Finland (former Academy of Finland)
Name of funding
-
Funding decision
-

Source database ID

WoS ID
WOS:000910959600001
Scopus ID
2-s2.0-85146068060
Other database ID
PMID: 36598465