Design, synthesis and evaluation of inhibitors of the SARS-CoV-2 nsp3 macrodomain

Approved

Classifications

MinEdu publication type
A1 Journal article (peer-reviewed)
Definition
Article
Target group
Scientific
Peer reviewed
Peer-reviewed
Article type
Journal article
Host publication type
Journal

Authors of the publication

Number of authors
15
Authors
Sherrill, Lavinia M.; Joya, Elva E.; Walker, AnnMarie; Roy, Anuradha; Alhammad, Yousef M.; Atobatele, Moriama; Wazir, Sarah; Abbas, George; Keane, Patrick; Zhuo, Junlin; Leung, Anthony K.L.; Johnson, David K.; Lehtiö, Lari; Fehr, Anthony R.; Ferraris, Dana

Publication channel information

Title of journal/series
Bioorganic and medicinal chemistry
ISSN (print)
0968-0896
ISSN (electronic)
1464-3391
ISSN (linking)
0968-0896
Publisher
Elsevier
Publication forum ID
52422
Publication forum level
1
Country of publication
Netherlands
Internationality
Yes

Detailed publication information

Publication year
2022
Reporting year
2022
Journal/series volume number
67
Article number
116788
DOI
10.1016/j.bmc.2022.116788
Language of publication
English

Co-publication information

International co-publication
Yes
Co-publication with a company
No

Availability

Classification and additional information

MinEdu field of science classification
1182 Biochemistry, cell and molecular biology
Keywords
SARS-CoV-2; Coronavirus; COVID-19; Nsp3 macrodomain inhibitors; ADP-ribosylation

Funding information

Funding information in the publication
This research was funded by National Institutes of Health (NIH) grants P20 GM113117, P30GM110761, a CTSA grant from NCATS awarded to the University of Kansas for Frontiers: University of Kansas Clinical and Translational Science Institute UL1TR002366 and University of Kansas start-up funds to A.R.F, and by Sidrid Jusélius foundation grant to L.L., and Johns Hopkins Bloomberg School of Public Health Discretionary Fund to A.K.L.L. DVF would like to acknowledge McDaniel College Student-Faculty Summer Research Fund, the Jean Richards Fund, the Schofield fund, and the Scott and Natalie Dahne fund.

Infrastructure information

Infrastructure information in the publication
LL would like to acknowledge the use of the facilities of the Biocenter Oulu Structural Biology core facility, a member of Biocenter Finland, Instruct-ERIC Centre Finland and FINStruct.

Source database ID

WoS ID
WOS:000811873300010
Scopus ID
2-s2.0-85130960934
Other database ID
PMID: 35597097